Equipment

Renishaw Raman microscope

  • Research-grade Raman microscope with flexible capabilities
  • Excitation Wavelength: 785nm
  • Spatial Resolution: Diameter of sampled region depends on the diffraction limited performance of the microscope objective (sub-um)
  • Spectral Resolution: Better than 1cm-1
  • Spectral Range: Raman fingerprint (350-1800 cm-1) @ 785nm excitation

Credit: CHUM

Handheld line scanning Raman system

  • First large field of view Raman imaging system designed to be integrated to the workflow of surgical cancer resection and in vivo tissue margin assessment
  • Excitation Wavelength: 785nm
  • Hyperspectral detection of the fingerprint Raman signal
  • Sterilizable with field of view is 1 cm2
  • Spatial resolution ~250 µm
  • Allows visualization of tissue structures under white-light reflectance

[1] F. Daoust et al., “A handheld macroscopic Raman spectroscopy imaging instrument for machine learning based molecular tissue margins characterization,” under review for publication in J. Biomed. Opt. (2020).

Mesoscopic Raman probe

  • Hand held stainless steel probe that can be used for immersion or direct contact measurements
  • Excitation Wavelength: 785nm, 671nm
  • Spatial Resolution: Diameter of sampled region is ~500um
  • Spectral Resolution: Better than 10cm-1
  • Spectral Range: Raman fingerprint (350-1800 cm-1) @ 785nm excitation; Raman high wavenumber (2500-4000 cm-1) @ 671nm excitation